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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KAT5 All Species: 19.09
Human Site: S477 Identified Species: 30
UniProt: Q92993 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92993 NP_006379.2 513 58582 S477 G Q Y I L T L S E D I V D G H
Chimpanzee Pan troglodytes XP_508558 546 61795 S510 G Q Y I L T L S E D I V D G H
Rhesus Macaque Macaca mulatta XP_001113038 442 50153 L412 P L S D L G L L S Y R S Y W S
Dog Lupus familis XP_540849 546 61797 S510 G Q Y I L T L S E D I V D G H
Cat Felis silvestris
Mouse Mus musculus Q8CHK4 513 58580 S477 G Q Y I L T L S E D I V D G H
Rat Rattus norvegicus Q5XI06 458 52614 S428 L V E E H L K S A Q Y K K P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q92021 609 68857 Y558 K I G V Y V D Y E G G Q I S F
Zebra Danio Brachydanio rerio NP_001013327 538 61712 S502 G Q Y I L T L S E D I V E G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960X4 541 61216 I505 K G Q Y I V C I N R V I I E Q
Honey Bee Apis mellifera XP_396552 453 52544 Q423 L N R E I I E Q H T A A M E K
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 I428 R Q V Y E K R I E A A K K K T
Sea Urchin Strong. purpuratus XP_786024 440 50807 D409 T L A K D V V D A H Q K A M S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 K415 H V I C A D P K V L D R H L K
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 R415 D I L D R Y N R L K A K K R R
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 L470 K I V V P E K L I K Q R E K S
Conservation
Percent
Protein Identity: 100 93.9 86.1 93.7 N.A. 99.8 37.2 N.A. N.A. N.A. 20.2 76.9 N.A. 56.5 59.2 44.4 60
Protein Similarity: 100 93.9 86.1 93.9 N.A. 100 53.2 N.A. N.A. N.A. 34.9 82.3 N.A. 67.2 71.5 59.8 70.1
P-Site Identity: 100 100 13.3 100 N.A. 100 6.6 N.A. N.A. N.A. 6.6 93.3 N.A. 0 0 13.3 0
P-Site Similarity: 100 100 13.3 100 N.A. 100 6.6 N.A. N.A. N.A. 13.3 100 N.A. 20 6.6 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 38.9 39.3 41.9
Protein Similarity: N.A. N.A. N.A. 54.5 55.9 58
P-Site Identity: N.A. N.A. N.A. 0 0 0
P-Site Similarity: N.A. N.A. N.A. 0 0 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 7 0 0 0 14 7 20 7 7 0 0 % A
% Cys: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 14 7 7 7 7 0 34 7 0 27 0 0 % D
% Glu: 0 0 7 14 7 7 7 0 47 0 0 0 14 14 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 34 7 7 0 0 7 0 0 0 7 7 0 0 34 0 % G
% His: 7 0 0 0 7 0 0 0 7 7 0 0 7 0 34 % H
% Ile: 0 20 7 34 14 7 0 14 7 0 34 7 14 0 0 % I
% Lys: 20 0 0 7 0 7 14 7 0 14 0 27 20 14 14 % K
% Leu: 14 14 7 0 40 7 40 14 7 7 0 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % M
% Asn: 0 7 0 0 0 0 7 0 7 0 0 0 0 0 0 % N
% Pro: 7 0 0 0 7 0 7 0 0 0 0 0 0 7 7 % P
% Gln: 0 40 7 0 0 0 0 7 0 7 14 7 0 0 7 % Q
% Arg: 7 0 7 0 7 0 7 7 0 7 7 14 0 7 7 % R
% Ser: 0 0 7 0 0 0 0 40 7 0 0 7 0 7 20 % S
% Thr: 7 0 0 0 0 34 0 0 0 7 0 0 0 0 7 % T
% Val: 0 14 14 14 0 20 7 0 7 0 7 34 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 34 14 7 7 0 7 0 7 7 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _